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Health screening: which tests do I need?

Prevention is always better than cure, but it can feel impossible to know where to start. We explain the most important health screening tests by age, what a private health MOT includes, and how regular check-ups can catch problems before they become serious.

AtWell Clinical Team -- AtWell Health Screening Service
March 2026
7 min read
Health screening: which tests do I need?

Why health screening matters

Many of the most serious health conditions develop silently. High blood pressure, raised cholesterol, prediabetes, early-stage cancers, thyroid dysfunction — none of these announce themselves with dramatic symptoms in their early stages. By the time you feel something is wrong, the window for simple, effective intervention may already have narrowed.

Regular health screening changes that. It shifts the relationship between patient and doctor from reactive to proactive — finding problems early, when they are easiest to treat, and giving you the information you need to make meaningful changes before a condition becomes a crisis. For working adults with busy lives, an annual or biennial check-up is one of the most valuable investments you can make in your long-term health.

AtWell offers comprehensive health screening packages designed to give you a complete picture — not a tick-box exercise, but a genuinely thorough assessment with time to discuss your results and what they mean.

The NHS health check: what it covers and what it misses

The NHS offers a free Health Check for adults aged 40 to 74 every five years. It covers blood pressure, cholesterol, BMI, blood sugar (for diabetes risk), and a brief cardiovascular risk calculation. For many people it is a useful prompt, but it has clear limitations: it is only available in a specific age range, it is offered infrequently, and the scope is relatively narrow.

A private health MOT goes considerably further. Depending on the package, it can include a full blood count, liver and kidney function tests, thyroid function, iron studies, vitamin levels, hormone panels, inflammatory markers, and — for relevant age groups — cancer markers. Combined with a clinical consultation and physical examination, it gives a far more detailed picture than any five-yearly questionnaire.

Key screening tests by age

Different ages carry different health risks, and screening should reflect this. Here is a broad guide to the most important tests at each life stage.

20s and 30s

  • Blood pressure — hypertension is increasingly common in younger adults and almost always symptom-free.
  • Cholesterol and lipid profile — especially important with a family history of heart disease.
  • Full blood count — checking for anaemia, infections, and platelet abnormalities.
  • Thyroid function (TSH) — thyroid disorders are particularly common in women and often missed.
  • STI screening — sexual health checks for sexually active adults.
  • Cervical screening — available on the NHS from age 25; smear tests every 3 years initially.
  • Mental health baseline — a conversation about mood, sleep, anxiety, and stress.

40s

  • HbA1c (diabetes screen) — risk increases with age, weight, and family history.
  • Liver function tests — particularly relevant for those who drink alcohol, take regular medication, or carry excess weight.
  • Hormonal health — for women, this is often the decade when perimenopause begins; testosterone levels may also decline for men.
  • Skin check — irregular moles or lesions warrant assessment.
  • Eye pressure (glaucoma risk) — often included in comprehensive eye examinations.
  • Bowel cancer screening awareness — family history may warrant earlier investigation.

50s and beyond

  • Bowel cancer screening — NHS offers FIT tests from age 50; colonoscopy referral for positive results.
  • Prostate-specific antigen (PSA) — a screening conversation for men; the test is imperfect but has a role in informed decision-making.
  • DEXA bone density scan — particularly relevant for post-menopausal women.
  • Cardiovascular risk assessment — a comprehensive calculation using cholesterol, blood pressure, HbA1c, and lifestyle factors.
  • Abdominal aortic aneurysm (AAA) screening — offered to men at 65 on the NHS; private screening can be arranged earlier with risk factors.

Blood tests explained

Blood tests form the backbone of any health screening programme. AtWell's blood testing service offers a wide range of panels with results typically available within 24 to 48 hours. Here is what the most common tests actually measure:

  • Full blood count (FBC) — looks at red cells (anaemia), white cells (infection, immune function), and platelets (clotting).
  • Urea and electrolytes (U&Es) — kidney function, fluid balance, and electrolyte levels including sodium, potassium, and creatinine.
  • Liver function tests (LFTs) — assesses liver enzymes and bilirubin, indicating liver health and bile duct function.
  • Lipid profile — total cholesterol, LDL ("bad"), HDL ("good"), and triglycerides. Used to calculate cardiovascular risk.
  • HbA1c — reflects average blood sugar levels over the past two to three months; the definitive test for diagnosing and monitoring diabetes.
  • Thyroid stimulating hormone (TSH) — a sensitive marker of thyroid function. Elevated TSH suggests hypothyroidism; suppressed TSH suggests hyperthyroidism.
  • Ferritin and iron studies — ferritin is the best marker of iron stores; iron deficiency is extremely common, particularly in women of reproductive age.
  • Vitamin D — deficiency is endemic in the UK, contributing to fatigue, low mood, bone loss, and impaired immune function.
  • CRP (C-reactive protein) — a marker of systemic inflammation, elevated in infection, autoimmune conditions, and cardiovascular risk.

What is included in a health MOT?

A comprehensive private health MOT typically combines a clinical consultation with a physical examination and a broad blood panel. Our health screening packages are designed to be genuinely thorough:

  • A 45-minute consultation with a GP to review your personal and family medical history
  • Physical examination including blood pressure, heart rate, weight, BMI, and where relevant, a cardiovascular and respiratory assessment
  • Comprehensive blood panel tailored to your age, sex, and risk factors
  • A detailed results appointment to discuss findings and agree any next steps
  • A written summary and personalised health recommendations

How often should I get screened?

There is no single right answer — it depends on your age, family history, lifestyle, and whether any concerns have already been identified. As a general guide:

  • Annually: Blood pressure, weight and BMI, mental health check-in. For people over 40, HbA1c and cholesterol annually is reasonable.
  • Every two to three years: Full health MOT for low-risk individuals under 40 with no significant family history.
  • Annually or more frequently: Anyone with a chronic condition, strong family history of cardiovascular disease or cancer, or who is taking regular medication.

If you are unsure what is right for you, a conversation with a GP is always the best starting point. AtWell's clinicians can help you build a personalised screening plan that reflects your individual risk profile.

"I had my AtWell health MOT thinking everything was fine. My Vitamin D was critically low and my thyroid was underactive — I had no idea. Within weeks of starting treatment, I felt like a different person."

-- Marcus L., Balsall Common

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